This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Codice: AN300598L_100μL | Marca: Elabscience | Confezionamento: 100μL

Specie: Human;Mouse;RatIsotipo: IgG,κClone: 1A8Coniugazione: Unconjugated
Dettagli prodotto
  • Codice: AN300598L_100μL
  • Marca: Elabscience
  • Specie target: Human;Mouse;Rat
  • Host: Rabbit
  • Concentrazione: 0.2 mg/mL
  • Link: Apri link
  • Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
  • Isotipo: IgG,κ
  • Clonalità: Monoclonal;Recombinant
  • Clone: 1A8
  • Coniugazione: Unconjugated
  • Applicazione: WB
  • Diluizione: WB 1:10000-1:20000
  • Simbolo target: Fascin
  • Ig target: Fan;FSCN;FSCN1;FAN1;HSN;SNL;p55;fascin;55 kDa actin-bundling protein;FSCN1;FAN1;HSN;SNL;p55;fascin;Singed-like protein
  • Area di ricerca: Signal Transduction