The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.

Codice: AN300681L_50μL | Marca: Elabscience | Confezionamento: 50μL

Specie: Human;Mouse;RatIsotipo: IgG,κClone: 6A2Coniugazione: Unconjugated

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Codice: AN300681L_50μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Rabbit
Concentrazione: 0.2 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG,κ
Clonalità: Monoclonal;Recombinant
Clone: 6A2
Coniugazione: Unconjugated
Applicazione: WB
Diluizione: WB 1:2000-1:10000
Simbolo target: BMAL1
Ig target: JAP;MOP;MIC;Pgp;CDW;BMAL;PASD;CSPG;bHLHe;MDU;ARNTL;BMAL1;BMAL1c;JAP3;MOP3;PASD3;TIC;bHLHe5;aryl hydrocarbon receptor nuclear translocator like;IN;LHR;MC56;MDU2;MDU3;MIC4;Pgp1;CDW44;CSPG8;HCELL;HUTCH-I;ECMR-III;ARNT like protein 1 brain and muscle;Aryl hydrocarbon receptor nuclear translocator like protein 1;Aryl hydrocarbon receptor nuclear translocator-like protein 1;Basic helix loop helix PAS orphan MOP3;Basic helix loop helix PAS protein MOP3;Basic-helix-loop-helix-PAS protein MOP3;bHLH PAS protein JAP3;bHLH-PAS protein JAP3;BMAL 1;Brain and muscle ARNT like 1;Brain and muscle ARNT-like 1;CG8727 PA;Class E basic helix-loop-helix protein 5;cycle;JAP 3;Member of PAS protein 3;Member of PAS superfamily 3;MGC47515;MOP 3;PAS domain-containing protein 3;PASD 3
Area di ricerca: Cardiovascular;Epigenetics and Nuclear Signaling;Neuroscience;Metabolism

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