Matrix metallopeptidase 2(MMP2) Homo sapiens This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis.

Dettagli prodotto

• Codice: AN300712L_100μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.2 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: 12G7
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:2000-1:10000;
• Simbolo target: MMP2
• Ig target: TBE;CLG;Matrix Metalloproteinase;MMP;CLG4;CLG4A;MMP-2;MMP-II;MONA;TBE-1;MMP2;72 kDa Gelatinase;72 kDa Type IV Collagenase;Gelatinase A;Matrix Metalloproteinase-2;72kD type IV collagenase;72kDa gelatinase;72kDa type IV collagenase);CLG 4;CLG 4A;Collagenase Type 4 alpha;Collagenase type IV A;Gelatinase alpha;Gelatinase neutrophil;Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase;Matrix Metalloproteinase 2;Matrix metalloproteinase 2 (gelatinase A;Matrix metalloproteinase II;MMP 2;MMP II;Neutrophil gelatinase;PEX;TBE 1;MMP-2
• Area di ricerca: Cardiovascular;Cancer;Cell Biology;Metabolism