Tumor protein p63(TP63) Homo sapiens This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrim.

Codice: AN300715L_50μL | Marca: Elabscience | Confezionamento: 50μL

Specie: Human;Mouse;RatIsotipo: IgG,κClone: 12G10Coniugazione: Unconjugated

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Codice: AN300715L_50μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Rabbit
Concentrazione: 0.2 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG,κ
Clonalità: Monoclonal;Recombinant
Clone: 12G10
Coniugazione: Unconjugated
Applicazione: WB
Diluizione: WB 1:2000-1:10000
Simbolo target: p63
Ig target: OFC;EEC;SHFM;AIS;B(p51A);B(p51B);EEC3;KET;LMS;NBP;OFC8;RHS;SHFM4;TP53CP;TP53L;TP73L;p40;p51;p53CP;p63;p73H;p73L;TP63;Amplified in squamous cell carcinoma;Chronic ulcerative stomatitis protein;CUSP;DN p63 alpha 1;DNp63;id:ibd3516;Keratinocyte transcription factor;Keratinocyte transcription factor KET;MGC115972;MGC192897;OTTHUMP00000209732;OTTHUMP00000209733;OTTHUMP00000209734;OTTHUMP00000209735;OTTHUMP00000209737;OTTHUMP00000209738;OTTHUMP00000209739;OTTHUMP00000209740;OTTHUMP00000209741;OTTHUMP00000209742;OTTHUMP00000209743;OTTHUMP00000209744;P51/P63;p53-related protein p63;TAp63alpha;Transformation related protein 63;Transformation-related protein 63;Trp53rp1;Trp63;Tumor protein 63;Tumor protein p53-competing protein;Tumor protein p53-like;tumor protein p63;Tumor protein p63 deltaN isoform delta;Tumor protein p73;Tumor protein p73-like;AIS;B(p51A);B(p51B);EEC3;KET;LMS;NBP;OFC8;p40;p51;p53CP;p63;p73H;p73L;RHS;SHFM4;TP53CP;TP53L;TP63;TP73L;p40/p63
Area di ricerca: Cell Biology;Epigenetics and Nuclear Signaling;Cancer

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