The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG,κ
Clonalità: Monoclonal;Recombinant
Clone: 8B5
Coniugazione: Unconjugated
Applicazione: WB;IHC
Diluizione: IHC 1:200-1:1000;WB 1:2000-1:10000
Simbolo target: ATG5
Ig target: ATG;APG;hAPG;Autophagy protein;ATG5;APG5;APG5-LIKE;APG5L;ASP;hAPG5;Apoptosis-specific protein;Autophagy protein 5;APG 5;APG 5L;APG5 autophagy 5 like;APG5 like;Apoptosis specific protein;ATG 5;ATG5 autophagy related 5 homolog;Autophagy related 5;Homolog of S Cerevisiae autophagy 5;OTTHUMP00000040507
Area di ricerca:Cell Biology;Cardiovascular;Cancer;Metabolism
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