This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Codice: AN300969L_50μL | Marca: Elabscience | Confezionamento: 50μL

Specie: Human;Mouse;RatIsotipo: IgG,κClone: 10A3Coniugazione: Unconjugated

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Codice: AN300969L_50μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Rabbit
Concentrazione: 0.2 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG,κ
Clonalità: Monoclonal;Recombinant
Clone: 10A3
Coniugazione: Unconjugated
Applicazione: WB
Diluizione: WB 1:1000-1:5000
Simbolo target: NRAS
Ig target: ALPS;HRAS;NRAS;ALPS4;CMNS;N-ras;NCMS;NRAS1;NS6;GTPase NRas;GTPase;HRAS1;RASN;Transforming protein N-Ras;AV095280;N ras;N ras protein part 4;Neuroblastoma RAS viral (v ras) oncogene homolog;OTTHUMP00000013879;OTTMUSP00000023521;Transforming protein N Ras;v ras neuroblastoma RAS viral oncogene homolog;N-RAS
Area di ricerca: Signal Transduction;Epigenetics and Nuclear Signaling;Cancer;Tags & Cell Markers

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