This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Dettagli prodotto

• Codice: AN301003L_100μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.2 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: 12B9
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: IHC 1:500-1:2000;WB 1:500-1:2000
• Simbolo target: TLS
• Ig target: ETM;ALS;POMP;HNRNPP;FUS;ALS6;ETM4;FUS1;HNRNPP2;POMP75;TLS;RNA-binding protein FUS;ALS6;ETM4;FUS1;HNRNPP2;POMP75;RNA-binding protein FUS;TLS;16) in malignant liposarcoma);16) malignant liposarcoma;75 kDa DNA pairing protein;75 kDa DNA-pairing protein;Amyotrophic lateral sclerosis 6;FUS CHOP;Fus like protein;Fused in sarcoma;Fusion (involved in t(12;Fusion derived from t(12;Fusion gene in myxoid liposarcoma;Heterogeneous nuclear ribonucleoprotein P2;hnRNP P2;Oncogene FUS;Oncogene TLS;RNA binding protein FUS;TLS CHOP;Translocated in liposarcoma;Translocated in liposarcoma protein
• Area di ricerca: Epigenetics and Nuclear Signaling;Cancer