This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

Dettagli prodotto

• Codice: AN301101L_100μL
• Marca: Elabscience
• Specie target: Human;Rat
• Host: Rabbit
• Concentrazione: 0.2 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: 6A10
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:1000-5000
• Simbolo target: SIRT1
• Ig target: SIR;HST;SIRT;Hsir;homolog-like;SIR2 like protein;Regulatory protein SIR2 homolog;NAD-dependent deacetylase sirtuin;Sirtuin (silent mating type information regulation 2 homolog);SIR2L;Hsirt;75SirT;sirtuin;SIRT1;SIR2;SIR2L1;SIR2alpha;sirtuin 1;75SirT1;Hsir2;Hsirt1;HST2;S.cerevisiae;NAD-dependent deacetylase sirtuin-1;Regulatory protein SIR2 homolog 1;SIR2 like protein 1;homolog-like 1;SirtT1 75 kDa fragment;Sirtuin (silent mating type information regulation 2 homolog) 1;SIR2;SIR2alpha;SIR2L1;sirtuin 1;homolog of;NAD dependent deacetylase sirtuin 1;NAD dependent protein deacetylase sirtuin 1;OTTHUMP00000198111;OTTHUMP00000198112;S. cerevisiae;SIR1;SIR2 like 1;SIR2-like protein 1;Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae);Sirtuin type 1
• Area di ricerca: Cell Biology;Epigenetics and Nuclear Signaling;Microbiology;Tags & Cell Markers;Metabolism