This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG,κ
Clonalità: Monoclonal;Recombinant
Clone: 11D10
Coniugazione: Unconjugated
Applicazione: WB;IHC
Diluizione: IHC 1:200-1000;WB 1:1000-5000
Simbolo target: RhoA
Ig target: ARH;RHOH;ARH12;ARHA;RHO12;RHOH12;Rho;RHOA;EDFAOB;ARH12;EDFAOB;RHO12;RHOH12;Aplysia ras related homolog 12;H 12;H12;Oncogene RHO H12;ras homolog family member A;Ras homolog gene family member A;Rho A;Rho cDNA clone 12;RHO H12;Small GTP binding protein Rho A;Transforming protein Rho A;Transforming protein RhoA;Rho A
Area di ricerca:Signal Transduction;Cancer
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