The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Dettagli prodotto

• Codice: AN301143L_50μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.2 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: 6H4
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:2000-1:10000;
• Simbolo target: CaMKII α, β
• Ig target: KIAA;CAMK2A;CAMKA;KIAA0968;Alpha CaMKII;Calcium calmodulin dependent protein kinase II;Calcium/calmodulin dependent protein kinase II alpha B subunit;Calcium/calmodulin dependent protein kinase type II alpha chain;Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha;Calcium/calmodulin-dependent protein kinase II alpha;Calcium/calmodulin-dependent protein kinase II-alpha;Calcium/calmodulin-dependent protein kinase type II subunit alpha;Calcium/calmodulin-dependent protein kinase type IIA;CaM kinase II alpha chain;CaM kinase II alpha subunit;CaM kinase II subunit alpha;CaMK II alpha subunit;CaMKII;CaMK-II subunit alpha;CaMKIINalpha;EC 2.7.11.17;KCC2A;MGC123320;MGC139375;MGC155201;mKIAA0968;PK2CDD;PKCCD;R74975;zgc:112538;zgc:123320;CaMKIIα/β
• Area di ricerca: Neuroscience;Signal Transduction;Cardiovascular;Cancer;Metabolism