DROSHA(drosha ribonuclease III) Homo sapiens This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.

Codice: AN301162L_100μL | Marca: Elabscience | Confezionamento: 100μL

Specie: Human;Mouse;RatIsotipo: IgG,κClone: 11G11Coniugazione: Unconjugated

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Codice: AN301162L_100μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Rabbit
Concentrazione: 0.2 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG,κ
Clonalità: Monoclonal;Recombinant
Clone: 11G11
Coniugazione: Unconjugated
Applicazione: WB;IHC
Diluizione: IHC 1:200-1:1000;WB 1:2000-1:10000
Simbolo target: Drosha
Ig target: ETOHI;DROSHA;ETOHI2;HSA242976;RANSE3L;RN3;RNASE3L;RNASEN;Drosha double stranded RNA specific endoribonuclease;Drosha ribonuclease type III;Nuclear RNase III Drosha;p241;Protein Drosha;Putative protein p241 which interacts with transcription factor Sp1;Putative ribonuclease III;Ribonuclease 3;Ribonuclease III;Ribonuclease III nuclear;Ribonuclease type III nuclear;RibonucleaseIII;RN 3;RNase 3;RNase III;RNase3;RnaseⅢ;RNaseIII;RNC;Drosha
Area di ricerca: Epigenetics and Nuclear Signaling

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