NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Dettagli prodotto

• Codice: AN301332L_100μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.2 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: 9A4
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:2000-1:10000;
• Simbolo target: NF-κB p65
• Ig target: NFKB;Transcription factor p;Nuclear factor of kappa light polypeptide gene enhancer in B-cells;NF-kB p;NFKB3;p65;NF-kB p65;RELA;CMCU;Transcription factor p65;Nuclear factor NF-kappa-B p65 subunit;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3;NFKB3;p65;transcription factor p65;Avian reticuloendotheliosis viral (v rel) oncogene homolog A;MGC131774;NF kappa B p65delta3;Nuclear Factor NF Kappa B p65 Subunit;Nuclear factor of kappa light polypeptide gene enhancer in B cells 3;OTTHUMP00000233473;OTTHUMP00000233474;OTTHUMP00000233475;OTTHUMP00000233476;OTTHUMP00000233900;p65 NF kappaB;p65 NFkB;TF65;V rel avian reticuloendotheliosis viral oncogene homolog A;v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65));V rel reticuloendotheliosis viral oncogene homolog A;v rel reticuloendotheliosis viral oncogene homolog A (avian);NFkB p65
• Area di ricerca: Cell Biology;Neuroscience;Microbiology;Signal Transduction;Epigenetics and Nuclear Signaling;Cancer;Cardiovascular;Metabolism