Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5). Involved in the regulation of myeloid cell differentiation.

Dettagli prodotto

• Codice: AN301516L_100μL
• Marca: Elabscience
• Specie target: Human;
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A215
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:100-1:1000
• Simbolo target: c-erbB-3/HER-3
• Ig target: HER;LCCS;Proto-oncogene-like protein c-ErbB;Tyrosine kinase-type cell surface receptor HER;MDA-BF;p180-ErbB;p45-sErbB;p85-sErbB;ERBB3;ErbB-3;HER3;LCCS2;MDA-BF-1;c-erbB-3;c-erbB3;erbB3-S;p180-ErbB3;p45-sErbB3;p85-sErbB3;Proto-oncogene-like protein c-ErbB-3;Tyrosine kinase-type cell surface receptor HER3;EEBB3
• Area di ricerca: Signal Transduction;Cancer