The distal upstream original binding protein 1 (FUBP1) is a single-stranded DNA-binding protein that can sometimes bind to single-stranded RNA. FUBP1 is a transactivator of the proto-oncogene c-myc transcription process, that is, FUBP1 binds to the upstream element FUSE of the housekeeping gene c-myc promoter to enhance the transcription of c-myc, thereby promoting cell proliferation, and in the formation of tumors Has an important role.
