MYL3, also named as MLC1v, is an essential light chain of myosin that is associated with muscle contraction. It is expressed in ventricular and slow skeletal muscle. MYL3 may serve as a target for caspase-3 in dying cardiomyocytes. Mutations of MYL3 gene cause hypertrophic cardiomyopathy. MYL3 has been identified as potential serum biomarker for drug induced myotoxicity. Great increase in MYL3 serum concentration has been observed in rats with cardiac and skeletal muscle injury.

Dettagli prodotto

• Codice: AN301607L_50μL
• Marca: Elabscience
• Specie target: Human;Rat;Mouse
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A310
• Coniugazione: Unconjugated
• Applicazione: WB;IHC;FCM
• Diluizione: WB 1:500-1:2000;IHC 1:200-1:1000;FCM 1:50-1:100
• Simbolo target: Myosin Light Chain 3
• Ig target: Myl;MYL3;alkali;Cardiac myosin light chain 1;CMH8;CMLC1;ELC of myosin;Essential light chain of myosin;light chain 1;light chain 3;light polypeptide 3;MLC1SB;MLC1V;Myosin;Myosin light chain 1;Myosin light chain 1 slow;Myosin light chain 1 slow twitch muscle B/ventricular isoform;Myosin light chain 3;OTTHUMP00000165922;skeletal;slow;Slow skeletal ventricular myosin alkali light chain 3;slow-twitch muscle B/ventricular isoform;ventricular;Ventricular/slow twitch myosin alkali light chain;VLC1
• Area di ricerca: Signal Transduction;Cardiovascular