Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein.

Dettagli prodotto

• Codice: AN301683L_50μL
• Marca: Elabscience
• Specie target: Human;
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A386
• Coniugazione: Unconjugated
• Applicazione: WB;IHC;IF
• Diluizione: WB 1:500-1:1000;IHC 1:200-1:1000;IF 1:50
• Simbolo target: RMP/C19orf2
• Ig target: NNX;PPP1R;C19orf;C19orf2;NNX3;PPP1R19;RMP;URI;URI1;prefoldin-like chaperone;Chromosome 19 open reading frame 2;NNX3;NNX3 protein;Protein NNX3;Protein phosphatase 1 regulatory subunit 19;RMP;RNA polymerase II subunit 5 mediating protein;RNA polymerase II subunit 5-mediating protein;RPB5 mediating protein;RPB5-mediating protein;Unconventional prefoldin RPB5 interactor;Unconventional prefoldin RPB5 interactor 1
• Area di ricerca: Epigenetics and Nuclear Signaling