S100A1 is a member of the S100 protein family, each of which contains two EF-hand calcium-binding motifs. These proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. At least 13 S100 genes are clustered on chromosome 1q21. S100A1 may function in stimulation of Ca<sup>2+</sup>-induced Ca<sup>2+</sup> release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Ig target: S100A;S100A1;Bpb;NEF;Protein S100-A1;S100;S100 alpha;S100 beta;S100 calcium binding protein A1;S100 calcium binding protein B;S100 calcium-binding protein A1;S-100 protein alpha chain;S100 protein alpha polypeptide;S-100 protein subunit alpha;S100-alpha;S100B;S100beta;S10A1
Area di ricerca:Neuroscience;Signal Transduction;Tags & Cell Markers
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