The CD40 antigen is a 44-48 kDa type I integral membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. This antigen is found on B cell lines, is strongly expressed by interdigitating cells (IDC), basal epithelial cells, and is also present on macrophages, some endothelial cells, and follicular dendritic cells. It is a well-known regulator of T cell immunity including in cancer. CD40-ligand, primarily expressed on activated T cells, interacts with CD40 on APCs resulting in a ‘licensed’ state.

Dettagli prodotto

• Codice: AN301709L_50μL
• Marca: Elabscience
• Specie target: Human;
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A417
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:1000-1:5000;IHC 1:200-1:1000
• Simbolo target: CD40
• Ig target: CDW;B-cell surface antigen CD;Tumor necrosis factor receptor superfamily member;TNFRSF;CD40;Bp50;CDW40;TNFRSF5;p50;Tumor necrosis factor receptor superfamily member 5;B-cell surface antigen CD40;CD40L receptor;TNFRSF5;AI326936;B cell associated molecule CD40;B cell surface antigen CD40;B cell-associated molecule;CD 40;CD40 (protein);CD40 antigen;CD40 antigen (TNF receptor superfamily member 5);CD40 molecule;CD40 protein;CD40 type II isoform;GP39;HIGM1;IGM;IMD3;isoform CRA_a;member 5;MGC9013;Nerve growth factor receptor related B lymphocyte activation molecule;OTTHUMP00000031699;OTTHUMP00000031700;TBAM;T-BAM;TNF receptor superfamily member 5;TNR5;TRAP;Tumor necrosis factor receptor superfamily;Tumor necrosis factor receptor superfamily member 5 precursor
• Area di ricerca: Immunology;Cardiovascular;Stem Cells