Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2. It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator (By similarity.

Codice: AN301720L_100μL | Marca: Elabscience | Confezionamento: 100μL

Specie: Human;MouseIsotipo: IgG,κClone: A428Coniugazione: Unconjugated
Dettagli prodotto
  • Codice: AN301720L_100μL
  • Marca: Elabscience
  • Specie target: Human;Mouse
  • Host: Rabbit
  • Concentrazione: 1 mg/mL
  • Link: Apri link
  • Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
  • Isotipo: IgG,κ
  • Clonalità: Monoclonal;Recombinant
  • Clone: A428
  • Coniugazione: Unconjugated
  • Applicazione: WB;IF;IP
  • Diluizione: WB 1:1000-1:2000;IF 1:50;IP 1:25-1:50
  • Simbolo target: BOB-1/OBF-1
  • Ig target: BOB;POU2AF;OBF;POU2AF1;BOB1;OBF-1;OBF1;OCAB;POU2AF1;BOB1;OBF-1;OBF1;OCAB
  • Area di ricerca: Immunology;Epigenetics and Nuclear Signaling