HMGA1 a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. HMGA1 preferentially binds to the minor groove of AT-rich regions in double-stranded DNA.
Ig target: HMGA;HMGA1;HMG-R;HMGA1A;HMGIY;High mobility group (nonhistone chromosomal) protein isoforms I and Y;High mobility group AT hook 1;High mobility group AT-hook protein 1;High mobility group protein 1;High mobility group protein A1;High mobility group protein HMG-I/HMG-Y;High mobility group protein Ia;High mobility group protein R;HMG R;HMG-I(Y);MGC12816;MGC4242;MGC4854;Nonhistone chromosomal high mobility group protein HMG I/HMG Y
Area di ricerca:Microbiology;Epigenetics and Nuclear Signaling;Cancer
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