ATG4B is a member of the autophagin protein family. Its cysteine protease activity is required for the cytoplasm to vacuole transport (Cvt) and autophagy. ATG4B cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.

Dettagli prodotto

• Codice: AN301739L_50μL
• Marca: Elabscience
• Specie target: Human;Rat;Mouse
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A447
• Coniugazione: Unconjugated
• Applicazione: WB;IHC;FCM
• Diluizione: WB 1:500-1:1000;IHC 1:200-1:1000;FCM 1:50-1:100
• Simbolo target: ATG4B
• Ig target: AUTL;KIAA;ATG4B;APG4B;AUTL1;cysteine protease ATG4B;KIAA0943;APG4B;AUTL1;cysteine protease ATG4B;APG4 autophagy 4 homolog B;ATG4 autophagy related 4 homolog B (S. cerevisiae);AUT like 1 cysteine endopeptidase;AUT-like 1 cysteine endopeptidase;Autophagin 1;Autophagin-1;Autophagy related 4B cysteine peptidase;Autophagy related cysteine endopeptidase 1;Autophagy related protein 4 homolog B;Autophagy-related cysteine endopeptidase 1;Autophagy-related protein 4 homolog B;hAPG4B;MGC1353
• Area di ricerca: Cancer;Cell Biology;Cardiovascular;Metabolism