Elongator Acetyltransferase Complex Subunit 4 (ELP4) is a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation involved in the pathway 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. The elongator complex catalyzes formation of carboxy methyluridine in the wobble base at position 34 in tRNAs. Diseases associated with ELP4 include Aniridia 2 and Coloboma of Optic Nerve. Among its related pathways are Mesodermal Commitment Pathway and Chromatin organization.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG,κ
Clonalità: Monoclonal;Recombinant
Clone: A478
Coniugazione: Unconjugated
Applicazione: WB;IF;IP
Diluizione: WB 1:500-1:1000;IF 1:50;IP 1:25-1:50
Simbolo target: ELP4
Ig target: ELP;Elongator complex protein;hELP;C11orf;dJ68P15A;dJ68P15A.1;Elongation protein 4 homolog;elongation protein 4 homolog (S. cerevisiae);Elongator complex protein 4;FLJ20498;hELP4;PAX6 neighbor gene protein;PAX6NEB;C11orf19;PAXNEB;ELP4;dJ68P15A.1
Area di ricerca:Epigenetics and Nuclear Signaling
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