This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

Dettagli prodotto

• Codice: AN301801L_50μL
• Marca: Elabscience
• Specie target: Human;
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A513
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:1000
• Simbolo target: PRAME
• Ig target: OIP;PRAME;CT130;MAPE;OIP-4;OIP4;4930534P07Rik;Cancer/testis antigen 130;Melanoma antigen preferentially expressed in tumors;OIP 4;OIP4;OPA interacting protein 4;Opa interacting protein OIP4;OPA-interacting protein 4;Preferentially expressed antigen in melanoma;Preferentially expressed antigen of melanoma;RP23-250F8.3
• Area di ricerca: Tags & Cell Markers;Epigenetics and Nuclear Signaling;Cancer