SUV39H2, also known as KMT1B, is a member of the SUV39 subfamily of lysine methyltransferases (KMTs) that plays a significant role in histone H3-K9 di-/Trimethylation, transcriptional regulation and cell cycle. Overexpressions of SUV39H2 at gene, mRNA and protein levels are known to be associated with a range of cancers: leukemia, lymphomas, lung cancer, breast cancer, colorectal cancer, gastric cancer, hepatocellular cancer and so on. Accumulating evidence indicates that SUV39H2 acts as an oncogene and contributes to the initiation and progression of cancers.

Dettagli prodotto

• Codice: AN301817L_50μL
• Marca: Elabscience
• Specie target: Human;Rat;Mouse
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A529
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:1000;IHC 1:50-1:100
• Simbolo target: SUV39H2
• Ig target: SUV39H;SUV39H2;KMT1B;FLJ23414;H3 K9 HMTase 2;H3-K9-HMTase 2;Histone H3 K9 methyltransferase 2;Histone H3-K9 methyltransferase 2;Histone lysine N methyltransferase H3 lysine 9 specific 2;Histone lysine N methyltransferase SUV39H2;Histone-lysine N-methyltransferase SUV39H2;Lysine N methyltransferase 1B;Lysine N-methyltransferase 1B;sSuppressor of variegation 3 9 homolog 2 (Drosophila);Su(var)3 9 Drosophila homolog of 2;Su(var)3 9 homolog 2;Su(var)3-9 homolog 2;Suppressor of variegation 3 9 homolog 2;Suppressor of variegation 3-9 homolog 2;SUV92
• Area di ricerca: Epigenetics and Nuclear Signaling