The Ret is a receptor tyrosine kinase that functions as a multicomponent receptor complex in conjunction with other membrane-bound, ligand-binding GDNF family receptors. Ligands that bind the Ret receptor include the glial cell line-derived neurotrophic factor (GDNF) and its congeners neurturin, persephin, and artemin. Research studies have shown that alterations in the corresponding RET gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma, and a congenital developmental disorder known as Hirschsprung’s disease.

Codice: AN301836L_50μL | Marca: Elabscience | Confezionamento: 50μL

Specie: Human;MouseIsotipo: IgG,κClone: A548Coniugazione: Unconjugated

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Codice: AN301836L_50μL
Marca: Elabscience
Specie target: Human;Mouse
Host: Rabbit
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG,κ
Clonalità: Monoclonal;Recombinant
Clone: A548
Coniugazione: Unconjugated
Applicazione: WB
Diluizione: WB 1:1000-1:5000
Simbolo target: Ret
Ig target: MTC;CDHF;CDHR;HSCR;Cadherin family member;RET-ELE;RET;CDHF12;CDHR16;HSCR1;MEN2A;MEN2B;MTC1;PTC;RET-ELE1;RET51;Cadherin family member 12;Proto-oncogene c-Ret;Proto-oncogene tyrosine-protein kinase receptor Ret;Proto-oncogene tyrosine-protein kinase receptor Ret;Cadherin family member 12;Proto-oncogene c-Ret
Area di ricerca: Signal Transduction;Cancer

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