IkB-beta a protein of the NF-kappa-B inhibitor family. IKB beta Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with IKB beta-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Codice: AN301851L_50μL | Marca: Elabscience | Confezionamento: 50μL

Specie: Human;MouseIsotipo: IgG,κClone: A563Coniugazione: Unconjugated

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Codice: AN301851L_50μL
Marca: Elabscience
Specie target: Human;Mouse
Host: Rabbit
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG,κ
Clonalità: Monoclonal;Recombinant
Clone: A563
Coniugazione: Unconjugated
Applicazione: WB;IF;FCM
Diluizione: WB 1:500-1:1000;FCM 1:50-1:100;IF 1:50-1:100
Simbolo target: IKB beta
Ig target: TRIP;NFKBIB;IKBB;TRIP9;I kappa B beta;IkappaBbeta;I-kappa-B-beta;IKB beta;IkB-B;IkBbeta;IkB-beta;NF kappa BIB;NF-kappa-B inhibitor beta;NF-kappa-BIB;Thyroid receptor interacting protein 9;Thyroid receptor-interacting protein 9;TR interacting protein 9;TR-interacting protein 9;TRIP-9
Area di ricerca: Signal Transduction;Epigenetics and Nuclear Signaling;Immunology

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