CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also known as GPR13 or V28. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12).

Dettagli prodotto

• Codice: AN301864L_100μL
• Marca: Elabscience
• Specie target: Human;
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A576
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:1000
• Simbolo target: CX3CR1
• Ig target: GPR;CCRL;GPRV;CX3CR;CMKDR;CMKBRL;CX3CR1;CCRL1;CMKBRL1;CMKDR1;GPR13;GPRV28;V28;Beta chemokine receptor-like 1;CMK-BRL1;CMK-BRL-1;CX3C chemokine receptor 1;C-X3-C CKR-1;C-X3-C motif chemokine receptor 1;fractalkine receptor;G-protein coupled receptor 13
• Area di ricerca: Microbiology;Tags & Cell Markers;Immunology;Neuroscience;Cancer