SMARCA2, also named as BRM, is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. SMARCA2 is involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

Dettagli prodotto

• Codice: AN301908L_50μL
• Marca: Elabscience
• Specie target: Human;Rat;Mouse
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A624
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:1000;IHC 1:500-1:3000
• Simbolo target: SMARCA2/BRM
• Ig target: SNF2L;SMARCA;BAF190B;BRM;SNF2A;SNF2L2;SMARCA2;ATP dependent helicase SMARCA2;ATP-dependent helicase SMARCA2;BAF190;BRG1-associated factor 190B;FLJ36757;Global transcription activator homologous sequence;hBRM;hSNF2a;MGC74511;Possible global transcription activator SNF2L2;Probable global transcription activator SNF2L2;Protein brahma homolog;SMCA2;SNF2 alpha;SNF2 like 2;SNF2/SWI2 like protein 2;SNF2-alpha;SNF2LA;Sth1p;Sucrose nonfermenting 2 like protein 2;SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
• Area di ricerca: Epigenetics and Nuclear Signaling