FoxC1, also named as FKHL7 or FREAC3, is one of two mammalian FoxC subfamily members. Along with FoxC2, it is expressed in paraxial mesoderm where it functions to promote somitogenesis, myogenesis, and vascular development, possibly under Wnt/β-catenin regulation. Mutations in FoxC1 are implicated in anterior segment dysgenesis (ASD) disorders, including congenital glaucoma and Axenfeld-Rieger syndrome. Research studies have shown that alterations in FoxC1 expression are linked to breast cancer invasiveness and have been shown to modulate proliferation and migration of breast cancer cells in vitro.

Codice: AN301947L_100μL | Marca: Elabscience | Confezionamento: 100μL

Specie: Human;Isotipo: IgG,κClone: A663Coniugazione: Unconjugated

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Codice: AN301947L_100μL
Marca: Elabscience
Specie target: Human;
Host: Rabbit
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG,κ
Clonalità: Monoclonal;Recombinant
Clone: A663
Coniugazione: Unconjugated
Applicazione: WB
Diluizione: WB 1:1000
Simbolo target: FOXC1
Ig target: IHG;FOXC;ASGD;FKHL;IRID;RIEG;FOXC1;ARA;ASGD3;FKHL7;FREAC-3;FREAC3;IGDA;IHG1;IRID1;RIEG3;FKH L7;FKHL 7;Forkhead (Drosophila) like 7;Forkhead box C1;Forkhead box protein C1;Forkhead drosophila homolog like 7;Forkhead like 7;Forkhead related activator 3;Forkhead related protein FKHL7;Forkhead related transcription factor 3;Forkhead-related protein FKHL7;Forkhead-related transcription factor 3;FOX C1;FOXC 1;FREAC 3;IHG 1;IRID 1;Iridogoniodysgenesis type 1;Myeloid factor delta
Area di ricerca: Epigenetics and Nuclear Signaling;Developmental Biology

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