C-type lectin domain family 2 member D (CLEC2D), also known as lectin-like transcript 1 (LLT1) and osteoclast inhibitory lectin (OCIL), is a type II transmembrane C-type lectin receptor primarily expressed upon immune cell activation in T cells, B cells, NK cells, and plasmacytoid and monocyte-derived dendritic cells. CLEC2D interacts with NKR-P1A (KLRB1, CD161) on NK cells and some subsets of T cells, inhibiting NK cell cytotoxicity while alternatively inducing proliferation and IFNγ production in T cells. CLEC2D is also expressed by osteoblasts, inhibiting osteoclast formation and bone resorption.

Dettagli prodotto

• Codice: AN301970L_50μL
• Marca: Elabscience
• Specie target: Human;
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A686
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:1000
• Simbolo target: CLEC2D
• Ig target: LLT;CLEC2D;CLAX;LLT1;OCIL;C type lectin related f;C type lectin superfamily 2;CLC2D;CLEC2D protein;Clec2d5;C-type lectin domain family 2 member D;L LT1;Lectin like NK cell receptor;Lectin like transcript 1;Lectin-like NK cell receptor;Lectin-like transcript 1;LLT-1;member D;Osteoclast inhibitory lectin
• Area di ricerca: Immunology