BAF53/ACTL6 proteins are highly homologous, actin-related proteins found in the SWI/SNF complex. In addition to the canonical SWI/SNF complex, BAF53A/ACTL6A is also member of the embryonic SWI/SNF complex, known as esBAF, which plays a role in pluripotency and development. BAF53B/ACTL6B is a member of the neural-specific SWI/SNF complex that facilitates binding to target genes and is involved in memory and synaptic plasticity. BAF53/ACTL6 has been shown to interact with c-Myc, where it functions as a cofactor and is important in the transformation process. Further studies have shown ACTL6/BAF53 is associated with EMT and transformation in various cancers.

Dettagli prodotto

• Codice: AN302040L_50μL
• Marca: Elabscience
• Specie target: Human;Rat;Mouse
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A760
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:5000
• Simbolo target: BAF53B
• Ig target: ACTL;ACTL6;BAF53B;ACTL6B;53 kDa BRG1 associated factor B;53 kDa BRG1-associated factor B;ACL 6B;ACL6B;Actin like 6;Actin like protein 6B;Actin like protein6B;Actin related protein;Actin related protein Baf53b;actin-like 6B;Actin-like protein 6B;Actin-related protein Baf53b;Actl 6;ACTL 6B;ACTL6 B;Arp Na;ArpN a;ArpN alpha;ArpNa;ArpNalpha;Baf 53b;BRG1-associated factor 53B
• Area di ricerca: Neuroscience;Epigenetics and Nuclear Signaling;Stem Cells