The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Dettagli prodotto

• Codice: E-AB-10092_20μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.3 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:1000-1:5000;IHC 1:50-1:200
• Simbolo target: BAK1
• Ig target: Apoptosis regulator BAK;BAK;BAK like;Bak NT;BAK;Bak1;Bcl 2 homologous antagonist/killer;Bcl 2 like 7 protein;Bcl-2 homologous antagonist/killer;Bcl-2-like protein 7;BCL2 antagonist/killer 1;Bcl2 like 7 Protein;Bcl2-L-7;BCL2L7;CDN1;Cell death inhibitor 1;MGC117255;MGC3887;NBak;Pro apoptotic protein BAK
• Area di ricerca: Cancer;Cell Biology