The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain

Codice: E-AB-10116_200μL | Marca: Elabscience | Confezionamento: 200μL

Specie: Human;Mouse;RatIsotipo: IgGConiugazione: Unconjugated
Dettagli prodotto
  • Codice: E-AB-10116_200μL
  • Marca: Elabscience
  • Specie target: Human;Mouse;Rat
  • Host: Rabbit
  • Concentrazione: 0.4 mg/mL
  • Link: Apri link
  • Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
  • Isotipo: IgG
  • Clonalità: Polyclonal
  • Coniugazione: Unconjugated
  • Applicazione: WB;IHC
  • Diluizione: WB 1:500-1:2000;IHC 1:50-1:200
  • Simbolo target: AARS2
  • Ig target: AARS 2;AARS2;AARSL;Alanine tRNA ligase 2 mitochondrial;Alanine tRNA ligase;Alanyl tRNA synthetase 2 mitochondrial;Alanyl tRNA synthetase like;AlaRS;bA444E17.1;COXPD8;Gm89;KIAA1270;LKENP;MGC69820;MT ALARS;MTALARS;Probable alanyl tRNA synthetase mitochondrial;RP11-444E17.1
  • Area di ricerca: Epigenetics and Nuclear Signaling