The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.

Dettagli prodotto

• Codice: E-AB-10125_20μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.3 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:2000;IHC 1:50-1:200
• Simbolo target: ALDOA
• Ig target: ALDA;Aldo1;ALDOA;ALDOA;Aldolase 1;Aldolase A;Aldolase A fructose bisphosphatase;Aldolase A fructose bisphosphate;Aldolase;fructose-bisphosphate A;Epididymis secretory sperm binding protein Li 87p;FRUCTOALDOLASE A;Fructose 1 6 bisphosphate triosephosphate lyase;Fructose bisphosphate aldolase A;Fructose bisphosphate aldolase;FRUCTOSE-1;6-BISPHOSPHATE ALDOLASE A;Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase A Muscle-type;GSD12;HEL S 87p;Lung cancer antigen NY LU 1;Lung cancer antigen NY-LU-1;MGC10942;MGC17716;MGC17767;Muscle type aldolase;Muscle-type aldolase;RNALDOG5
• Area di ricerca: Cancer;Metabolism;Signal Transduction