The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Codice: E-AB-10260_20μL | Marca: Elabscience | Confezionamento: 20μL

Specie: HumanIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-10260_20μL
Marca: Elabscience
Specie target: Human
Host: Rabbit
Concentrazione: 0.3 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB;IHC
Diluizione: WB 1:500-1:2000;IHC 1:50-1:200
Simbolo target: CRTAM
Ig target: CD355;Class I MHC restricted T cell associated molecule;Class-I MHC-restricted T-cell-associated molecule;CRTAM;CRTAM;Cytotoxic and regulatory T cell molecule;Cytotoxic and regulatory T-cell molecule
Area di ricerca: Immunology

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