This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Dettagli prodotto

• Codice: E-AB-10477_200μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.3 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:1000-1:5000;IHC 1:50-1:200
• Simbolo target: MUTYH
• Ig target: A/G specific adenine DNA glycosylase;A/G-specific adenine DNA glycosylase;Adenine DNA glycosylase;CYP2C;hMYH;MGC4416;MutY (E. coli) homolog;MutY homolog (E. coli);MutY homolog;MutY;E. coli;homolog of;Mutyh;MUTYH;MYH;rMYH
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling