This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Dettagli prodotto

• Codice: E-AB-10525_20μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.5 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: PARD6A
• Ig target: 0710008C04Rik;2610010A15Rik;Par 6 partitioning defective 6 C elegans homolog alpha;Par 6 partitioning defective 6 homolog alpha;Par 6 partitioning defective 6 homolog alpha C elegans;PAR 6A;PAR-6 alpha;PAR-6;par-6 family cell polarity regulator alpha;PAR-6A;PAR6;PAR6A;PAR6alpha;PAR6C;Pard6a;Partitioning defective 6 homolog alpha;partitioning-defective protein 6;partitioning-defective protein 6; C. elegans;homolog of;alpha;Tax interacting protein 40;Tax interaction protein 40;TAX40;TIP 40;TIP-40;TIP40
• Area di ricerca: Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Signal Transduction;Stem Cells