Resistin-like betais aproteinthat in humans is encoded by theRETNLBgene. An infusion of either resistin or RELMB in rats rapidly induced severe hepatic but not peripheral insulin resistance. Increases in circulating resistin or RELMB levels markedly stimulated hepatic glucose production despite the presence of fixed physiologic insulin levels. This enhanced rate of glucose output was due to increased flux through glucose-6-phosphatase. The results supported the notion that a novel family of fat- and gut-derived circulating proteins modulates hepatic insulin action.

Dettagli prodotto

• Codice: E-AB-10579_200μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.3 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: RETNLB
• Ig target: C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 2;CCGR;Colon and small intestine specific cysteine rich protein;Colon and small intestine-specific cysteine-rich protein;Colon carcinoma related gene protein;Colon carcinoma-related gene protein;Cysteine rich secreted A12 alpha like protein 1;Cysteine rich secreted protein A12 alpha like 1;Cysteine rich secreted protein FIZZ2;Cysteine-rich secreted protein A12-alpha-like 1;Cysteine-rich secreted protein FIZZ2;FIZZ1;FIZZ2;Found in inflammatory zone 1;HXCP2;RELM beta;RELMb;RELMbeta;Resistin like beta;Resistin like protein beta;Resistin-like beta;RETNB;RETNL2;Retnlb;XCP2
• Area di ricerca: Cancer;Signal Transduction