The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

Codice: E-AB-10712_20μL | Marca: Elabscience | Confezionamento: 20μL

Specie: Human;MouseIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-10712_20μL
Marca: Elabscience
Specie target: Human;Mouse
Host: Rabbit
Concentrazione: 0.2 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB
Diluizione: WB 1:500-1:2000
Simbolo target: ACMSD
Ig target: 2 amino 3 carboxymuconate 6 semialdehyde decarboxylase;2-amino-3-carboxymuconate-6-semialdehyde decarboxylase;acmsd;ACMSD;Aminocarboxymuconate semialdehyde decarboxylase;Picolinate carboxylase
Area di ricerca: Cancer;Metabolism;Signal Transduction

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