C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro.

Codice: E-AB-10816_60μL | Marca: Elabscience | Confezionamento: 60μL

Specie: HumanIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-10816_60μL
Marca: Elabscience
Specie target: Human
Host: Rabbit
Concentrazione: 0.5 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: APLF
Ig target: 2010301N04Rik;AI452191;Aplf;APLF;Aprataxin and PNK-like factor;Apurinic-apyrimidinic endonuclease APLF;C2orf13;PNK and APTX like FHA protein;PNK and APTX-like FHA domain-containing protein;RGD1565557;XIP1;XRCC1 interacting protein 1;XRCC1-interacting protein 1
Area di ricerca: Epigenetics and Nuclear Signaling

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