Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family.

Dettagli prodotto

• Codice: E-AB-10953_200μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.3 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:2000;IHC 1:50-1:200
• Simbolo target: PIP4K2A
• Ig target: 1 phosphatidylinositol 4 phosphate 5 kinase 2 alpha;1 phosphatidylinositol 4 phosphate 5 kinase;1 phosphatidylinositol 4 phosphate kinase;1-phosphatidylinositol-5-phosphate 4-kinase 2-alpha;4 5 kinase B isoform;4 5 kinase C isoform;4 5 kinase isoform 2 alpha;Diphosphoinositide kinase 2 alpha;Diphosphoinositide kinase 2-alpha;FLJ13267;Phosphatidylinositol 4 phosphate 5 kinase type 2 alpha;Phosphatidylinositol 4 phosphate 5 kinase type II alpha;Phosphatidylinositol-5-phosphate 4-kinase type II alpha;Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha;PI(5)P 4-kinase type II alpha;PI42A;PI5P4KA;PIP4K2A;PIP4KII-alpha;PIP5K2;PIP5K2A;PIP5KII alpha;PIP5KII-alpha;PIP5KIIA;PIP5KIII;PIPK;PtdIns;PtdIns(4)P-5-kinase B isoform;PtdIns(4)P-5-kinase C isoform;PtdIns(5)P-4-kinase isoform 2-alpha;Type II phosphatidylinositol 4 phosphate 5 kinase 53 K isoform
• Area di ricerca: Cancer;Metabolism;Signal Transduction