This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Codice: E-AB-11318_120μL | Marca: Elabscience | Confezionamento: 120μL

Specie: HumanIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-11318_120μL
Marca: Elabscience
Specie target: Human
Host: Rabbit
Concentrazione: 0.2 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: ICAM4
Ig target: CD242;CD242 antigen;ICAM-4;Icam4;ICAM4;Intercellular adhesion molecule 4;Landsteiner Wiener blood group glycoprotein;Landsteiner-Wiener blood group glycoprotein;LW;LW blood group protein
Area di ricerca: Cancer;Cell Biology;Cardiovascular;Metabolism;Immunology;Signal Transduction

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