This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: NBL1
Ig target: D1S1733E;DAN;DAN domain family member 1;DAND 1;DAND1;Differential screening selected gene aberrant in neuroblastoma;MGC8972;NB;NBL 1;Neuroblastoma candidate region suppression of tumorigenicity 1;Neuroblastoma suppression of tumorigenicity 1;Neuroblastoma suppressor of tumorigenicity 1;NO 3;NO3;Zinc finger protein DAN
Area di ricerca:Cancer;Signal Transduction
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