This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Dettagli prodotto

• Codice: E-AB-11534_20μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.3 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:2000
• Simbolo target: RGS1
• Ig target: 1R20;B cell activation protein BL34;B-cell activation protein BL34;BL34;Early response protein 1R20;IER 1;IER1;Immediate early response 1 B cell specific;immediate-early response 1;B-cell specific;IR20;Regulator of G protein signalling 1;Regulator of G-protein signaling 1;RGS 1;RGS1;RGS1
• Area di ricerca: Signal Transduction