This gene is ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. May be play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:25-1:100
Simbolo target: ICOSLG
Ig target: B7 H2;B7 homolog 2;B7 homologue 2;B7 like protein Gl50;B7 related protein 1;B7-H2;B7-like protein Gl50;B7-related protein 1;B7H2;B7RP 1;B7RP-1;B7RP1;CD 275;CD275;CD275 antigen;GL 50;GL50;ICOS L;ICOS LG;ICOS ligand;ICOSL;ICOSL;Icoslg;Inducible T cell co stimulator ligand;KIAA0653;LICOS;Transmembrane protein B7 H2 ICOS ligand
Area di ricerca:Immunology
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