Leucine-rich repeats and immunoglobulin-like domains protein 1is aproteinthat in humans is encoded by theLRIG1gene.It encodes atransmembrane proteinthat has been shown to interact with receptor tyrosine kinases of theEGFR-family,METandRET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.

Dettagli prodotto

• Codice: E-AB-12544_200μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: LRIG1
• Ig target: Leucine rich repeat protein;Leucine rich repeat protein LRIG1;leucine rich repeats and immunoglobulin like domains 1;Leucine-rich repeats and immunoglobulin-like domains protein 1;leucine-rich repeats- and immunoglobulin-like domains-cotnaining protein 1;LIG 1;LIG-1;LIG1;Lrig1;LRIG1;Ortholog of mouse integral membrane glycoprotein LIG 1
• Area di ricerca: Cancer