This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Codice: E-AB-12546_120μL | Marca: Elabscience | Confezionamento: 120μL

Specie: Human;MouseIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-12546_120μL
Marca: Elabscience
Specie target: Human;Mouse
Host: Rabbit
Concentrazione: 0.6 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: LRP5
Ig target: BMND1;EVR1;EVR4;HBM;Low density lipoprotein receptor related protein 5;Low density lipoprotein receptor related protein 7;Low-density lipoprotein receptor-related protein 5;LR3;LRP-5;Lrp5;LRP5;LRP7;OPPG;OPS;OPTA1;Osteoporosis pseudoglioma syndrome;VBCH2
Area di ricerca: Cancer;Cardiovascular;Metabolism;Neuroscience;Signal Transduction;Stem Cells

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