This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Dettagli prodotto

• Codice: E-AB-12800_200μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.7 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:200-1:1000
• Simbolo target: NFATC2
• Ig target: AI607462;cytoplasmic 2;KIAA0611;NF ATc2;NF ATp;NF-ATc2;NF-ATp;NFAC2;NFAT 1;NFAT pre existing subunit;NFAT pre-existing subunit;NFAT transcription complex;preexisting component;NFAT1;NFAT1-D;NFATc2;NFATp;Nuclear factor of activated T cells cytoplasmic 2;Nuclear factor of activated T cells cytoplasmic calcineurin dependent 2;Nuclear factor of activated T cells pre-existing component;Nuclear factor of activated T cells;preexisting component;Nuclear factor of activated T-cells;Preexisting nuclear factor of activated T cells 2;T cell transcription factor NFAT 1;T-cell transcription factor NFAT1
• Area di ricerca: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism;Immunology;Signal Transduction