The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.

Dettagli prodotto

• Codice: E-AB-12931_20μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.4 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: CELSR2
• Ig target: Cadherin EGF LAG seven pass G type receptor 2 flamingo Drosophila homolog;Cadherin EGF LAG seven-pass G-type receptor 2;Cadherin family member 10;CDHF10;CELR2;Celsr2;EGF like domain multiple 2;EGF-like protein 2;EGFL2;epidermal growth factor like 2;Epidermal growth factor-like protein 2;Flamingo homolog 3;Flamingo1;KIAA0279;MEGF3;Multiple EGF-like domains protein 3;Multiple epidermal growth factor-like domains 3;Multiple epidermal growth factor-like domains protein 3
• Area di ricerca: Cancer;Neuroscience;Signal Transduction