Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Dettagli prodotto

• Codice: E-AB-12998_60μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.5 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: ATG4B
• Ig target: APG4 autophagy 4 homolog B;APG4B;ATG4 autophagy related 4 homolog B (S. cerevisiae);ATG4B;ATG4B;AUT like 1 cysteine endopeptidase;AUT-like 1 cysteine endopeptidase;AUTL1;Autophagin 1;Autophagin-1;Autophagy related 4B cysteine peptidase;Autophagy related cysteine endopeptidase 1;Autophagy related protein 4 homolog B;Autophagy-related cysteine endopeptidase 1;Autophagy-related protein 4 homolog B;Cysteine protease ATG4B;hAPG4B;MGC1353
• Area di ricerca: Cancer;Cell Biology;Cardiovascular;Metabolism;Signal Transduction